Ipamorelin is a synthetic peptide and a so-called “growth hormone secretagogue” that selectively stimulates the release of growth hormone (GH) through activation of the ghrelin receptor. It is being researched for its potential effects on recovery, body composition, sleep quality, and metabolic function and is distinguished by its selective GH-releasing activity with minimal influence on other hormones.
Ipamorelin is a synthetic pentapeptide that acts as a selective agonist of the ghrelin receptor (GHSR-1a) in research. It is considered the most selective GHRP because it stimulates GH release without a significant increase in cortisol, prolactin, or ACTH in research models.
The Ipamorelin lyophilisate is produced according to high quality standards and verified with HPLC to a purity of ≥ 99%.
Research relevance
Selective GH release — models requiring a clean GH signal without cortisol/prolactin interference.
GHSR-1α receptor — study of selectivity within the ghrelin receptor family.
Synergy with GHRH analogs — often evaluated in combination with CJC-1295 or Sermorelin for enhanced GH pulses.
Sleep and recovery research — preclinical models regarding GH pulses during slow-wave sleep.
Frequently Asked Questions
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide agonist of the ghrelin receptor. In research, it is used for selective GH release without the off-target effects exhibited by other GHRPs.
Why is Ipamorelin considered the most selective GHRP?
Ipamorelin activates GHSR-1a with minimal influence on other pituitary hormones. Studies show that it stimulates GH release without a significant increase in cortisol, prolactin, or ACTH — making it unique for research questions where a clean GH signal is crucial.
What purity is guaranteed?
Janoshik validates every batch for HPLC purity ≥ 99%, with test results for heavy metals and endotoxins available via the COA.
How is Ipamorelin stored?
Store the lyophilisate refrigerated (2–8 °C), protected from light and moisture. Open vials only immediately before reconstitution for optimal peptide integrity.
Disclaimer: Intended solely for research purposes. Not intended for human or animal consumption, medical, diagnostic, therapeutic, or cosmetic applications. Buyer is 18+ and confirms the research context.
