Semaglutide

GLP-1 S is a synthetic GLP-1 receptor agonist used in laboratory research into glucose metabolism, energy regulation, and cell signaling pathways. Thanks to its strong binding affinity to the GLP-1 receptor, GLP-1 S is an important model molecule in metabolic and endocrine research. The product is manufactured in controlled laboratory environments and has a guaranteed purity of ≥ 99% (HPLC tested). Each batch is supplied as a stable lyophilisate, suitable for research where high accuracy and reproducibility are essential.

Research relevance

• GLP-1 receptor agonism — selective binding and activation of the GLP-1 receptor with picomolar affinity.
• Long half-life — due to C₁₈ fatty acid acylation and albumin binding, semaglutide has a half-life of approximately 1 week.

Frequently Asked Questions

What is Semaglutide?

Semaglutide is a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist (GLP-1 RA) used extensively in metabolic and obesity research. It is a synthetic peptide analogue of human GLP-1, modified to provide prolonged biological activity and enhanced stability. Lumo supplies a 500 mcg research-grade variant; commercial pharmaceutical products are available separately in higher dosages.

How does Semaglutide work?

Semaglutide activates GLP-1 receptors, mimicking the action of the naturally occurring incretin hormone GLP-1. In research settings, it is studied for its effects on glucose regulation, insulin secretion, glucagon suppression, gastric emptying, appetite signaling, and energy balance. Its molecular modifications extend circulation time compared with native GLP-1.

What purity is guaranteed?

HPLC validation for ≥ 99% purity; additional analysis for heavy metals and residual solvents.

How should Semaglutide be stored?

Store refrigerated at 2–8 °C in the original packaging, protected from light. Avoid repeated freeze-thaw cycles. For short-term handling, follow established laboratory storage protocols.

Disclaimer: Intended for research purposes only. Not intended for human or animal consumption, medical, diagnostic, therapeutic, or cosmetic applications. The buyer is 18+ and confirms the research context.