GHK-Cu is a naturally occurring copper-binding peptide (glycyl-L-histidyl-L-lysine copper complex) found in human plasma, saliva, and urine. It is known for its role in tissue regeneration, wound healing, and modulation of inflammation, and is being studied for applications in skin health, hair growth, and regenerative medicine.
GHK-Cu is a naturally occurring tripeptide-copper complex consisting of Glycine-Histidine-Lysine (GHK) chelated with a divalent copper ion (Cu²⁺). Within research, GHK-Cu is classically studied for its influence on collagen synthesis, tissue repair, and gene expression of extracellular matrix components.
The GHK-Cu lyophilisate is produced according to high quality standards and verified with HPLC for purity and degree of copper chelation.
Research relevance
Collagen and elastin synthesis — classic research tool for extracellular matrix modulation.
Wound healing models — preclinical studies on fibroblast proliferation and angiogenesis.
Gene expression modulation — research into the influence on several hundred genes related to skin repair and inflammation.
Antioxidant response — models related to SOD activity and ROS modulation.
Frequently Asked Questions
What is GHK-Cu?
GHK-Cu is an endogenous tripeptide (Gly-His-Lys) complexed with one copper ion. It occurs naturally in plasma, saliva, and urine, with decreasing concentrations in aging tissues.
Why is the copper ion essential?
The biological activity of GHK depends largely on Cu²⁺ chelation. The copper ion is required for redox-active properties and for binding to many cellular target proteins.
What purity is guaranteed?
Janoshik validates every batch for HPLC purity ≥ 99%, with additional analysis of copper stoichiometry, heavy metals, and endotoxins.
How is GHK-Cu stored?
Store the lyophilisate refrigerated (2–8 °C), protected from light and moisture. Stable for a long time under dry conditions; less stable in solution due to copper catalytic degradation. Disclaimer: Intended solely for research purposes. Not intended for human or animal consumption, medical, diagnostic, therapeutic, or cosmetic applications. Buyer is 18+ and confirms the research context.
