KPV

KPV, also known as Lys-Pro-Val, is a naturally occurring tripeptide derived from the C-terminal region of α-melanocyte-stimulating hormone (α-MSH). Despite consisting of only three amino acids, KPV retains several biological activities associated with α-MSH and is widely studied for its interaction with inflammatory signaling pathways and tissue repair mechanisms.

KPV lyophilisate is produced according to high quality standards and verified with HPLC to a purity of ≥ 99%.

Research relevance

• Inflammatory signaling — studied for its modulation of pro-inflammatory cytokine pathways, including TNF-α, IL-1β, and NF-κB.

• Intestinal barrier research — commonly investigated in experimental models of intestinal permeability and inflammatory bowel disease.

• Skin repair models — researched for its potential role in inflammatory skin conditions and tissue regeneration.

• Mucosal healing — evaluated in preclinical studies involving epithelial repair and wound healing.

Frequently Asked Questions

What is KPV?

KPV is a naturally occurring three-amino-acid peptide (Lys-Pro-Val) originating from the C-terminal sequence of α-MSH. It represents the minimal active fragment responsible for several of the parent hormone’s anti-inflammatory properties.

What purity is guaranteed?

Janoshik validates every batch for HPLC purity ≥ 99%, with additional analysis of heavy metals and endotoxins.

How is KPVstored?
Store the lyophilisate refrigerated (2–8 °C), protected from light and moisture. Open vials only immediately before reconstitution.

Disclaimer: Intended for research purposes only. Not intended for human or animal consumption, medical, diagnostic, therapeutic, or cosmetic uses. Buyer is 18+ and confirms the research context.